Design and integration of a multi-channel fluorescence detector

Xuan Ma, Adrian Grewe, Meike Kristina Hofmann, Martin Amberg, Stefan Sinzinger
  1. Fachgebiet Technische Optik, Technische Universität Ilmenau

xuan [dot] ma [at] tu-ilmenau [dot] de

In combination with fluidic systems, fluorescence detectors have a large variety of applications e.g. in biomedicine for ph-sensoring or the characterization of chemical reaction processes. Highly integrated and miniaturized optofluidic microsystems enable the handling of very small sample volumes in so-called segmented flow systems, which is beneficial for the practical application. A single-channel fluorescence sensor using planar integrated free space optical systems has been developed in the past. In order to increase the measuring flexibility and accuracy the extension to a multi-wavelength and multi-channel sensor system based on this concept is currently investigated. We present the concept, optical design and fabrication strategy of a highly integrated free space optical fluorescence detector for the application in a segmented-flow environment. The performance of the system is characterized and the application as a biochemical analysis system is discussed.

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@inproceedings{ma2012p1,
  author     = {Ma, Xuan and Grewe, Adrian and Hofmann, Meike Kristina and Amberg, Martin and Sinzinger, Stefan},
  title      = {{Design and integration of a multi-channel fluorescence detector}},
  booktitle  = {DGaO-Proceedings 2012},
  series     = {DGaO-Proceedings},
  eventtitle = {113. Jahrestagung der DGaO},
  eventdate  = {2012-05-30/2012-06-02},
  venue      = {Eindhoven},
  publisher  = {Deutsche Gesellschaft für angewandte Optik e.V.},
  year       = {2012},
  pages      = {P1},
  url        = {https://dgao-proceedings.de/paper/113-p1}
}
113. Jahrestagung der DGaO · Eindhoven · 2012